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MEG3 shuttled by exosomes released from human bone marrow mesenchymal stem cells promotes TP53 stability to regulate MCM5 transcription in keloid fibroblasts.

Feibin ZhuYuanjian YeYing ShaoChunli Xue
Published in: The journal of gene medicine (2024)
hBMSC-Exos delivered MEG3 to promote the protein stability of TP53, thereby activating MCM5 and promoting KF activity.
Keyphrases
  • endothelial cells
  • mesenchymal stem cells
  • stem cells
  • signaling pathway
  • resting state
  • induced pluripotent stem cells
  • pluripotent stem cells
  • protein protein
  • amino acid
  • binding protein