Reuterin isolated from the probiotic Lactobacillus reuteri promotes periodontal tissue regeneration by inhibiting Cx43-mediated the intercellular transmission of endoplasmic reticulum stress.

Nannan HanYitong LiuXiaoyan LiJuan DuLijia GuoYi Liu

Published in: Journal of periodontal research (2024)

Our findings identified reuterin isolated from extracts of the probiotic L. reuteri, which improves tissue regeneration and controls inflammation, thus providing a new therapeutic method for treating periodontitis.

Keyphrases

endoplasmic reticulum stress
stem cells
induced apoptosis
oxidative stress
lactic acid
signaling pathway
bacillus subtilis
wound healing