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Biochemical characterization of LR769, a new recombinant factor VIIa bypassing agent produced in the milk of transgenic rabbits.

Guillaume ChevreuxN TillyY LeblancC RamonV FaidM MartinF DhainautN Bihoreau
Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2017)
The innovative expression system used to produce LR769 yields a new safe and effective rhFVIIa for the treatment of haemophilia A or B patients with inhibitors.
Keyphrases
  • poor prognosis
  • binding protein
  • combination therapy