Sacubitril/valsartan and the risk of incident dementia in heart failure: a nationwide propensity-matched cohort study.

Hyun-Jung LeeHyung Kwan KimBong-Seong KimKyung-Do HanSoongu KwakChan Soon ParkTae-Min RheeJun-Bean ParkHeesun LeeYong-Jin Kim

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2023)

In a nationwide propensity-matched cohort of patients with heart failure, sacubitril/valsartan was not associated with an increased risk of incident dementia compared to ARBs. Sacubitril/valsartan and the risk of incident dementia in heart failure. ARB, angiotensin II receptor blocker; ARNI, angiotensin receptor neprilysin inhibitor.

Keyphrases

angiotensin ii
heart failure
angiotensin converting enzyme
mild cognitive impairment
cognitive impairment
ejection fraction
cardiovascular disease
vascular smooth muscle cells
left ventricular
cross sectional
type diabetes