Extracellular vesicles for acute kidney injury in preclinical rodent models: a meta-analysis.

Chao LiuJin WangJie HuBo FuZhi MaoHengda ZhangGuangyan CaiXiangmei ChenXuefeng Sun

Published in: Stem cell research & therapy (2020)

The present meta-analysis confirmed that EV therapy could improve renal function and the inflammatory response status and reduce cell apoptosis in a preclinical rodent AKI model. This provides important clues for human clinical trials on EVs.

Keyphrases

inflammatory response
systematic review
clinical trial
cell therapy
endothelial cells
acute kidney injury
meta analyses
cell proliferation
lipopolysaccharide induced
pluripotent stem cells
lps induced
stem cells
phase ii
bone marrow