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Cellular Processes Induced by HSV-1 Infections in Vestibular Neuritis.

Zhengdong ZhaoXiaozhou LiuYanjun ZongXinyu ShiYu Sun
Published in: Viruses (2023)
Herpesvirus is a prevalent pathogen that primarily infects human epithelial cells and has the ability to reside in neurons. In the field of otolaryngology, herpesvirus infection primarily leads to hearing loss and vestibular neuritis and is considered the primary hypothesis regarding the pathogenesis of vestibular neuritis. In this review, we provide a summary of the effects of the herpes virus on cellular processes in both host cells and immune cells, with a focus on HSV-1 as illustrative examples.
Keyphrases
  • hearing loss
  • herpes simplex virus
  • induced apoptosis
  • endothelial cells
  • cell cycle arrest
  • spinal cord
  • induced pluripotent stem cells
  • endoplasmic reticulum stress
  • pluripotent stem cells
  • spinal cord injury