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Quality Assurance for Multiplex Quantitative Clinical Chemistry Proteomics in Large Clinical Trials.

Esther ReijndersFred P H T M RomijnFigen ArslanJulien J J GeorgesMervin M PieterseEdwin R SchipperSonja Didden-BuitendijkMachteld C Martherus-BultmanNico P M SmitNina M DiederiksMaxim M TreepJohan Wouter JukemaChrista M CobbaertL Renee Ruhaak
Published in: The journal of applied laboratory medicine (2024)
This is the first study of its kind in which qCCP was performed at this scale. This research successfully demonstrates the feasibility of high-throughput LC-MS/MS applications in large clinical trials. ClinicalTrials.gov Registration Number: NCT01663402.
Keyphrases
  • clinical trial
  • high throughput
  • high resolution
  • open label
  • randomized controlled trial
  • phase iii
  • study protocol
  • double blind
  • real time pcr