[Laboratory signs of activation of the hemostasis system in patients with coronary heart disease, who had coronary artery bypass surgery.]

The hypercoagulable state is a risk factor for shunt thrombosis in patients who had coronary artery bypass surgery. That is why the study of factors and operative intervention which can lead to hypercoagulable states are extremely valuable and vital issues. 85 patients who had coronary artery bypass surgery were examined. 40 of them have 2 type diabetes mellitus. All patients underwent a study of the content of fibrinogen, soluble fibrin-monomer complexes, D-dimers, von Willebrand factor, induced platelet aggregation in the blood on the 14th day after the surgery. There were no significant differences in content of fibrinogen, soluble fibrin-monomer complexes, D-dimers, induced platelet aggregation in the blood between patients with diabetes mellitus and patient without diabetes mellitus. It was detected the connection between separate indicators of the hemostatic system studied and age, height, weight, waist circumference and how long ago myocardial infarction had occured. It was detected that indicators of induced platelet aggregation correlate with indicators of lipid metabolism and degree of coronary artery stenosis. According to the information received, progression of hypercoagulable state after coronary artery bypass surgery is depends on weight, waist circumference, age, how long ago myocardial infarction had occurred, indicators of lipid metabolism and degree of atherosclerotic cardiovascular disease of coronary arteries.