Application of a microdosed cocktail of 3 oral factor Xa inhibitors to study drug-drug interactions with different perpetrator drugs.

Gerd MikusKathrin I FoersterMarlene SchaumaekerMarie-Louise LehmannJürgen BurhenneWalter E Haefeli

Published in: British journal of clinical pharmacology (2020)

The microdosed FXaI cocktail approach is able to generate drug interaction data and can help elucidating the mechanism involved in the clearance of the different victim drugs. This is a safe approach to concurrently study drug-drug interactions with a drug class. (EudraCT 2016-003024-23).

Keyphrases

drug induced
adverse drug
emergency department
artificial intelligence