Gerd Mikus (G Mikus)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 41

Top Topics

Emergency Department

Top Venues

Clinical pharmacokinetics

British journal of clinical pharmacology

Clinical pharmacology and therapeutics

European journal of clinical pharmacology

This page only lists publications with an associated author ORCID identifier.

Publications

Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Anna M Mc Laughlin, Thomas Helland, Fenja Klima, Stijn L W Koolen, Ron H N van Schaik, Ron H J Mathijssen, Patrick Neven, Jesse Joachim Swen, Henk-Jan Guchelaar, Florence Dalenc, Melanie White-Koning, Robin Michelet, Gerd Mikus, Werner Schroth, Thomas Mürdter, Hiltrud B Brauch, Matthias Schwab, Håvard Søiland, Gunnar Mellgren, Fabienne Thomas, Charlotte Kloft, Daniel Louis Hertz, null null
Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort. Clinical pharmacology and therapeutics (2024)
Nicolas Hohmann, Anna S Friedrichs, Juergen Burhenne, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin. Clinical and translational science 17 (8) (2024)
Nicolas Hohmann, Anna S Friedrichs, Juergen Burhenne, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin. Clinical and translational science 17 (8) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics 63 (4) (2024)
Anna M Mc Laughlin, Thomas Helland, Fenja Klima, Stijn L W Koolen, Ron H N van Schaik, Ron H J Mathijssen, Patrick Neven, Jesse Joachim Swen, Henk-Jan Guchelaar, Florence Dalenc, Melanie White-Koning, Robin Michelet, Gerd Mikus, Werner Schroth, Thomas Mürdter, Hiltrud B Brauch, Matthias Schwab, Håvard Søiland, Gunnar Mellgren, Fabienne Thomas, Charlotte Kloft, Daniel Louis Hertz, null null
Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort. Clinical pharmacology and therapeutics 116 (3) (2024)
Brit S Rohr, Evelyn Krohmer, Kathrin I Foerster, Juergen Burhenne, Martin Schulz, Antje Blank, Gerd Mikus, Walter Emil Haefeli
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Clinical pharmacokinetics (2024)
Amin Muhareb, Antje Blank, Andreas Daniel Meid, Kathrin I Foerster, Felicitas Stoll, Juergen Burhenne, Walter Emil Haefeli, Gerd Mikus
CYP3A and CYP2C19 Activity Determined by Microdosed Probe Drugs Accurately Predict Voriconazole Clearance in Healthy Adults. Clinical pharmacokinetics (2023)
Franziska Kluwe, Robin Michelet, Wilhelm Huisinga, Markus Zeitlinger, Gerd Mikus, Charlotte Kloft
Towards Model-Informed Precision Dosing of Voriconazole: Challenging Published Voriconazole Nonlinear Mixed-Effects Models with Real-World Clinical Data. Clinical pharmacokinetics (2023)
Jason van Leuven, Simon Evans, Ganessan Kichenadasse, Neeltje Steeghs, Billie Bonevski, Gerd Mikus, Madelé van Dyk
Framework for Implementing Individualised Dosing of Anti-Cancer Drugs in Routine Care: Overcoming the Logistical Challenges. Cancers 15 (13) (2023)
Mareile H Breithaupt, Evelyn Krohmer, Lenka Taylor, Eva Körner, Torsten Hoppe-Tichy, Juergen Burhenne, Kathrin I Foerster, Markus Dachtler, Gerald Huber, Rakesh Venkatesh, Karin Eggenreich, David Czock, Gerd Mikus, Antje Blank, Walter Emil Haefeli
Time course of CYP3A activity during and after metamizole (dipyrone) in healthy volunteers. British journal of clinical pharmacology (2023)
Evelyn Krohmer, Brit Silja Rohr, Felicitas Stoll, Katja S Gümüs, Mariano Bergamino, Gerd Mikus, Max Sauter, Juergen Burhenne, Johanna Weiss, Andreas Daniel Meid, David Czock, Antje Blank, Walter Emil Haefeli
Influence of a Short Course of Ritonavir Used as Booster in Antiviral Therapies Against SARS-CoV-2 on the Exposure of Atorvastatin and Rosuvastatin. Cardiovascular drugs and therapy (2023)
Annika Elbe, Kathrin Isabelle Foerster, Antje Blank, Peter Rose, Jürgen Burhenne, Walter Emil Haefeli, Gerd Mikus
Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans. European journal of clinical pharmacology 78 (6) (2022)
Yomna M Nassar, Nicolas Hohmann, Robin Michelet, Katharina Gottwalt, Andreas D Meid, Jürgen Burhenne, Wilhelm Huisinga, Walter Emil Haefeli, Gerd Mikus, Charlotte Kloft
Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion. Clinical pharmacokinetics 61 (11) (2022)
Mareile H Breithaupt, Evelyn Krohmer, Lenka Taylor, Eva Koerner, Torsten Hoppe-Tichy, Juergen Burhenne, Kathrin I Foerster, Markus Dachtler, Gerald Huber, Rakesh Venkatesh, Karin Eggenreich, David Czock, Gerd Mikus, Antje Blank, Walter Emil Haefeli
Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers. European journal of clinical pharmacology 78 (12) (2022)
Josefine Schulz, Antonia Thomas, Ayatallah Saleh, Gerd Mikus, Charlotte Kloft, Robin Michelet
Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism. Pharmaceutics 14 (3) (2022)
Manuela Vay, Marleen Julia Meyer, Antje Blank, Gisela Skopp, Peter Rose, Mladen Vassilev Tzvetkov, Gerd Mikus
Oral Yohimbine as a New Probe Drug to Predict CYP2D6 Activity: Results of a Fixed-Sequence Phase I Trial. Clinical pharmacokinetics 59 (7) (2021)
Brit Silja Rohr, Kathrin Isabelle Foerster, Antje Blank, Jürgen Burhenne, Mazyar Mahmoudi, Walter Emil Haefeli, Gerd Mikus
Perpetrator Characteristics of Azole Antifungal Drugs on Three Oral Factor Xa Inhibitors Administered as a Microdosed Cocktail. Clinical pharmacokinetics (2021)
Anna M Mc Laughlin, Robin Michelet, Ferdinand Weinelt, Charlotte Kloft, Gerd Mikus
CYP2D6 phenotype explains reported yohimbine concentrations in four severe acute intoxications. Archives of toxicology 95 (8) (2021)
Kathrin I Foerster, Simon Hermann, Gerd Mikus, Walter Emil Haefeli
Drug-Drug Interactions with Direct Oral Anticoagulants. Clinical pharmacokinetics 59 (8) (2021)
Franziska Kluwe, Robin Michelet, Anna M Mc Laughlin, Corinna Maier, Lena Klopp-Schulze, Madelé van Dyk, Gerd Mikus, Wilhelm Huisinga, Charlotte Kloft
Perspectives on Model-Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations. Clinical pharmacology and therapeutics 109 (1) (2020)
Gerd Mikus, Kathrin I Foerster, Marlene Schaumaeker, Marie-Louise Lehmann, Jürgen Burhenne, Walter E Haefeli
Application of a microdosed cocktail of 3 oral factor Xa inhibitors to study drug-drug interactions with different perpetrator drugs. British journal of clinical pharmacology 86 (8) (2020)
Mazyar Mahmoudi, Kathrin I Foerster, Jürgen Burhenne, Johanna Weiss, Gerd Mikus, Walter Emil Haefeli
Application of Microdosed Intravenous Omeprazole to Determine Hepatic CYP2C19 Activity. Journal of clinical pharmacology 61 (6) (2020)
Brit Silja Rohr, Gerd Mikus
Proposal of a Safe and Effective Study Design for CYP3A-Mediated Drug-Drug Interactions. Journal of clinical pharmacology 60 (10) (2020)
Sabrina T Wiebe, Andreas D Meid, Gerd Mikus
Composite midazolam and 1'-OH midazolam population pharmacokinetic model for constitutive, inhibited and induced CYP3A activity. Journal of pharmacokinetics and pharmacodynamics 47 (6) (2020)
Gerd Mikus, Kathrin I Foerster, Marlene Schaumaeker, Marie-Louise Lehmann, Jürgen Burhenne, Walter E Haefeli
Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug-Drug Interactions with Potential Perpetrator Drugs. Clinical pharmacokinetics 58 (9) (2020)
Jana Grass, Peter Rose, Jürgen Burhenne, Antje Blank, Walter Emil Haefeli, Gerd Mikus
Absolute Bioavailability of Microdosed Midazolam After Buccal Administration Is Dependent on Buccal Exposure Time. Journal of clinical pharmacology 61 (4) (2020)
Sabrina T Wiebe, Andreas Huennemeyer, Werner Kadus, Markus Goettel, Alen Jambrecina, Armin Schultz, Richard Vinisko, Laura Schlieker, Lena Herich, Gerd Mikus
Midazolam microdosing applied in early clinical development for drug-drug interaction assessment. British journal of clinical pharmacology 87 (1) (2020)
Victoria C Ziesenitz, Janelle D Vaughns, Gilbert Koch, Gerd Mikus, Johannes N van den Anker
Pharmacokinetics of Fentanyl and Its Derivatives in Children: A Comprehensive Review. Clinical pharmacokinetics 57 (2) (2019)
Josefine Schulz, Franziska Kluwe, Gerd Mikus, Robin Michelet, Charlotte Kloft
Novel insights into the complex pharmacokinetics of voriconazole: a review of its metabolism. Drug metabolism reviews 51 (3) (2019)
Gerd Mikus
Probes and Cocktails for Drug-Drug Interaction Evaluation: The Future Is Microdosing? Clinical pharmacology and therapeutics 105 (6) (2019)
Nicolas Hohmann, Antje Blank, Jürgen Burhenne, Yosuke Suzuki, Gerd Mikus, Walter Emil Haefeli
Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses. British journal of clinical pharmacology 85 (10) (2019)
Manuela Vay, Kathrin I Foerster, Mazyar Mahmoudi, Jessica Seeßle, Gerd Mikus
No alteration of voriconazole concentration by plasmapheresis in a critically ill patient. European journal of clinical pharmacology 75 (2) (2018)
Christina Gade, K Dalhoff, T S Petersen, T Riis, C Schmeltz, E Chabanova, H R Christensen, Gerd Mikus, J Burhenne, J C Holm, H Holst
Higher chlorzoxazone clearance in obese children compared with nonobese peers. British journal of clinical pharmacology 84 (8) (2018)
Andrea Huppertz, Lars Werntz, Andreas Daniel Meid, Kathrin I Foerster, Juergen Burhenne, David Czock, Gerd Mikus, Walter Emil Haefeli
Rivaroxaban and macitentan can be coadministered without dose adjustment but the combination of rivaroxaban and St John's wort should be avoided. British journal of clinical pharmacology 84 (12) (2018)
Manuela Vay, Marius Majewsky, Gerd Mikus
Isotopically labelled paroxetine standard allows for definite structure elucidation of the paroxetine tandem mass spectrum. Rapid communications in mass spectrometry : RCM 32 (15) (2018)
Christina Gade, Kim Dalhoff, Tonny Petersen, Troels Riis, Camilla Schmeltz, Elizaveta Chabanova, Hanne Rolighed Christensen, Gerd Mikus, Juergen Burhenne, Jens Christian Holm, Helle Holst
Obesity-induced CYP2E1 activity in children. British journal of clinical pharmacology 85 (2) (2018)
Nicolas Hohmann, Rebecca Kreuter, Antje Blank, Johanna Weiss, Jürgen Burhenne, Walter E Haefeli, Gerd Mikus
Autoinhibitory properties of the parent but not of the N-oxide metabolite contribute to infusion rate-dependent voriconazole pharmacokinetics. British journal of clinical pharmacology 83 (9) (2017)
Andreas Daniel Meid, Sarah Mächler, Walter E Haefeli, Gerd Mikus
Real-world complexity of atrial fibrillation treatment with oral anticoagulants: design and interpretation of pharmacoepidemiological studies. British journal of clinical pharmacology 83 (10) (2017)
Nicolas Hohmann, Anna Maus, Alexandra Carls, Walter E Haefeli, Gerd Mikus
St. John's wort treatment in women bears risks beyond pharmacokinetic drug interactions. Archives of toxicology 90 (4) (2015)