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SNHG18 controls vascular smooth muscle cell contractile phenotype and neointimal hyperplasia.

Kaiyuan NiuChengxin ZhangMei YangEithne Margaret MaguireZhenning ShiShasha SunJianping WuChenxin LiuWeiwei AnXinxin WangShan GaoShenglin GeQingzhong Xiao
Published in: Cardiovascular research (2024)
We demonstrate that SNHG18 is a novel regulator in governing VSMC contractile phenotype and preventing injury-induced neointimal hyperplasia. Our findings have important implications for therapeutic targeting snhg18/miR-22-3p signalling in vascular diseases.
Keyphrases
  • smooth muscle
  • poor prognosis
  • single cell
  • long non coding rna
  • high glucose
  • diabetic rats
  • transcription factor
  • cancer therapy
  • drug delivery
  • bone marrow