SNHG18 controls vascular smooth muscle cell contractile phenotype and neointimal hyperplasia.
Kaiyuan NiuChengxin ZhangMei YangEithne Margaret MaguireZhenning ShiShasha SunJianping WuChenxin LiuWeiwei AnXinxin WangShan GaoShenglin GeQingzhong XiaoPublished in: Cardiovascular research (2024)
We demonstrate that SNHG18 is a novel regulator in governing VSMC contractile phenotype and preventing injury-induced neointimal hyperplasia. Our findings have important implications for therapeutic targeting snhg18/miR-22-3p signalling in vascular diseases.