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Validation of a spatial agent-based model for Taenia solium transmission ("CystiAgent") against a large prospective trial of control strategies in northern Peru.

Ian W PrayFrancesco PizzituttiGabrielle BonnetEloy A Gonzales-GustavsonWayne WakelandWilliam K PanWilliam E LambertArmando E GonzalezHector H GarciaSeth E O'Nealnull null
Published in: PLoS neglected tropical diseases (2021)
The validation of CystiAgent represented an important step towards developing an accurate and reliable T. solium transmission model that can be deployed to fill critical gaps in our understanding of T. solium transmission and control. To improve model accuracy, future versions would benefit from improved data on pig immunity and resistance, field effectiveness of anti-helminthic treatment, and factors driving spatial clustering of T. solium infections including dispersion and contact with T. solium eggs in the environment.
Keyphrases
  • randomized controlled trial
  • clinical trial
  • study protocol
  • high resolution
  • single cell
  • big data
  • electronic health record
  • mass spectrometry
  • machine learning
  • phase ii
  • artificial intelligence