Contrasting the brain imaging features of MOG-antibody disease, with AQP4-antibody NMOSD and multiple sclerosis.
Silvia MessinaRomina MarianoAdriana Roca-FernandezAna CaveyMaciej JurynczykMaria Isabel LeiteMassimiliano CalabreseMark JenkinsonJacqueline PalacePublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2021)
MOGAD patients are left with grey matter damage, and this may be related to persistent white matter lesions. NMOSD-AQP4 patients showed a relative sparing of deep grey matter volumes, but reduced non-lesional tissue FA. Observations from our study can be used to identify new markers of damage for future multicentre studies.
Keyphrases
- white matter
- multiple sclerosis
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- clinical trial
- oxidative stress
- randomized controlled trial
- patient reported outcomes
- study protocol
- mass spectrometry
- blood brain barrier
- minimally invasive
- current status
- robot assisted
- drug induced