Polyploid Giant Cancer Cells Generated from Human Cytomegalovirus-Infected Prostate Epithelial Cells.

Fidaa BouezzedineRanim El Baba Sandy Haidar AhmadGeorges Herbein

Published in: Cancers (2023)

HCMV-induced Myc and EZH2 upregulation coupled with stemness and EMT traits in IE1-expressing CTP might highlight the potential role of HCMV in PCa development and encourage the use of anti-EZH2 and anti-HCMV in PCa treatment.

Keyphrases

epithelial mesenchymal transition
endothelial cells
prostate cancer
high glucose
long non coding rna
stem cells
long noncoding rna
diabetic rats
epstein barr virus
cell proliferation
transcription factor
genome wide
drug induced
pluripotent stem cells
oxidative stress
replacement therapy
cancer stem cells
wild type