Late morbidity and mortality in adult survivors of childhood glioma with neurofibromatosis type 1: report from the Childhood Cancer Survivor Study.
Peter M K de BlankNan LiMichael J FisherNicole J UllrichSmita BhatiaYutaka YasuiCharles A SklarWendy LeisenringRebecca HowellKevin OeffingerKristina HardyM Fatih OkcuTodd M GibsonLeslie L RobisonGregory T ArmstrongKevin R KrullPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2020)
Late mortality among glioma survivors with NF1 is twice that of other survivors, due largely to subsequent malignancies. Screening, prevention, and early intervention for chronic health conditions and psychosocial and neurocognitive deficits may reduce long-term morbidity in this vulnerable population.