Inhibition of N-myc expression sensitizes human neuroblastoma IMR-32 cells expressing caspase-8 to TRAIL.
Myoung Woo LeeDae Seong KimHye Ryung KimHyun Jin ParkJi Won LeeKi Woong SungHong Hoe KooKeon Hee YooPublished in: Cell proliferation (2019)
N-myc and caspase-8 expressions are involved in TRAIL susceptibility in IMR-32 cells, and the combination of treatment with cisplatin and TRAIL may serve as a promising strategy for the development of therapeutics against neuroblastoma that is controlled by N-myc and caspase-8 expression.