The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease.

Ting-Yun ChenXiaoyun LiChing-Hsia HungHarinath BahudhanapatiJiangning TanDaniel J KassYingze Zhang

Published in: Molecular genetics & genomic medicine (2020)

Understanding the molecular mechanisms that drive aberrant expression of RXFP1 in disease and the functional roles of alternative splicing and receptor dimerization will provide insight into therapeutic targets that may restore the relaxin responsiveness of fibrotic tissues.

Keyphrases

human health
risk assessment
poor prognosis
binding protein
gene expression
systemic sclerosis
idiopathic pulmonary fibrosis