Neuroinflammation and Schizophrenia: New Therapeutic Strategies through Psychobiotics, Nanotechnology, and Artificial Intelligence (AI).
Freiser Eceomo Cruz MosqueraMaria Camila Guevara-MontoyaValentina Serna-RamirezYamil LiscanoPublished in: Journal of personalized medicine (2024)
The prevalence of schizophrenia, affecting approximately 1% of the global population, underscores the urgency for innovative therapeutic strategies. Recent insights into the role of neuroinflammation, the gut-brain axis, and the microbiota in schizophrenia pathogenesis have paved the way for the exploration of psychobiotics as a novel treatment avenue. These interventions, targeting the gut microbiome, offer a promising approach to ameliorating psychiatric symptoms. Furthermore, advancements in artificial intelligence and nanotechnology are set to revolutionize psychobiotic development and application, promising to enhance their production, precision, and effectiveness. This interdisciplinary approach heralds a new era in schizophrenia management, potentially transforming patient outcomes and offering a beacon of hope for those afflicted by this complex disorder.
Keyphrases
- artificial intelligence
- bipolar disorder
- machine learning
- big data
- deep learning
- traumatic brain injury
- randomized controlled trial
- lipopolysaccharide induced
- cerebral ischemia
- systematic review
- risk factors
- lps induced
- mental health
- cognitive impairment
- physical activity
- white matter
- cancer therapy
- subarachnoid hemorrhage
- sleep quality
- brain injury
- resting state
- blood brain barrier
- replacement therapy
- smoking cessation