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Phase I Study of Trifluridine/Tipiracil Plus Irinotecan and Bevacizumab in Advanced Gastrointestinal Tumors.

Anna M VargheseDana B CardinJonathan HerschAl B BensonHoward S HochsterLukas MakrisKensuke HamadaJordan D BerlinLeonard B Saltz
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Tolerability and activity observed in this phase I trial support further investigation of the FTD/TPI-irinotecan-bevacizumab combination in previously treated mCRC.
Keyphrases
  • metastatic colorectal cancer
  • open label
  • clinical trial
  • study protocol
  • phase iii
  • phase ii
  • randomized controlled trial
  • placebo controlled