Phase I Study of Trifluridine/Tipiracil Plus Irinotecan and Bevacizumab in Advanced Gastrointestinal Tumors.

Anna M VargheseDana B CardinJonathan HerschAl B BensonHoward S HochsterLukas MakrisKensuke HamadaJordan D Berlin Leonard B Saltz

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)

Tolerability and activity observed in this phase I trial support further investigation of the FTD/TPI-irinotecan-bevacizumab combination in previously treated mCRC.

Keyphrases

metastatic colorectal cancer
open label
clinical trial
study protocol
phase iii
phase ii
randomized controlled trial
placebo controlled