High Expression of PDLIM2 Predicts a Poor Prognosis in Prostate Cancer and Is Correlated with Epithelial-Mesenchymal Transition and Immune Cell Infiltration.
Songzhe PiaoLan ZhengHaihong ZhengMengya ZhouQin FengSuna ZhouMang KeHaihua YangXuequan WangPublished in: Journal of immunology research (2022)
Our study suggests that PDLIM family genes might be significantly correlated with oncogenesis and the progression of PRAD. PDLIM2 correlated with EMT and immune cell infiltration by acting as an oncogene in PRAD, which may serve as a potential prognostic biomarker for PRAD patients.
Keyphrases
- poor prognosis
- epithelial mesenchymal transition
- prostate cancer
- long non coding rna
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- transforming growth factor
- peritoneal dialysis
- prognostic factors
- signaling pathway
- gene expression
- patient reported outcomes
- climate change
- genome wide analysis