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Exploring Heterogeneity in Histology-Independent Technologies and the Implications for Cost-Effectiveness.

Peter MurphyLindsay ClaxtonRobert HodgsonDavid GlynnLucy BeresfordMatthew WaltonAlexis LlewellynStephen PalmerSofia Dias
Published in: Medical decision making : an international journal of the Society for Medical Decision Making (2021)
Central to the challenge of reimbursement of HITs is the potential for heterogeneity. This study illustrates how heterogeneity in clinical effectiveness can result in highly variable and uncertain estimates of cost-effectiveness. This analysis can help improve understanding of the consequences of histology-independent versus histology-specific decisions.
Keyphrases
  • single cell
  • randomized controlled trial
  • systematic review
  • human health