ATG3, a Target of miR-431-5p, Promotes Proliferation and Invasion of Colon Cancer via Promoting Autophagy.

Wei HuangChong ZengShanbiao HuLei WangJie Liu

Published in: Cancer management and research (2019)

Collectively, ATG3 upregulation, caused by downregulated miR-435-5p, promotes proliferation and invasion via an autophagy-dependent manner in colon cancer suggesting that miR-431-5p/ATG3/autophagy may be a potential therapeutic target in colon cancer.

Keyphrases

cell death
signaling pathway
endoplasmic reticulum stress
oxidative stress
cell proliferation
poor prognosis
risk assessment
long non coding rna