Experimental Reproduction of Dynamic Fluctuation of TSH Receptor-Binding Antibodies Between Stimulation and Inhibition.

Tetsuya TagamiKaho Hiroshima-HamanakaHironobu UmakoshiMika Tsuiki-NaruseToru KusakabeNoriko Satoh-AsaharaAkira ShimatsuKenji Moriyama

Published in: Journal of the Endocrine Society (2019)

Our studies suggest that the characteristics of TSHR-Abs in the patient serum can be mimicked by mixtures of human mAbs to the TSHR, stimulating, blocking, and neutral if any.

Keyphrases

endothelial cells
case report
induced pluripotent stem cells
ionic liquid
binding protein
pluripotent stem cells
case control