Leptin gene polymorphism (rs7799039; G2548A) is associated with changes in serum lipid concentrations during pregnancy: a prospective cohort study.

Dayana Rodrigues FariasNadya Helena Alves-SantosIlana EshriquiMaisa Cruz MartinsCláudio J StruchinerJaqueline LepschNathalia CostaGilberto Kac

Published in: European journal of nutrition (2019)

Women homozygous for the A allele of the leptin SNP (G2548A) had a higher increase in TG concentrations per gestational week compared with women with the AG or GG genotype. This is an exploratory and hypothesis-generating study, and the results need confirmation in studies with larger sample sizes.'

Keyphrases

pregnancy outcomes
weight gain
pregnant women
polycystic ovary syndrome
genome wide
quantum dots
clinical trial
fatty acid
metabolic syndrome
gene expression
type diabetes
adipose tissue
dna methylation
highly efficient
weight loss
case control
visible light