Safety Profile of Seven-Day Intra-articular Antibiotic Irrigation for the Treatment of Chronic Periprosthetic Joint Infection: A Prospective Randomized Phase II Comparative Study.
Bryan D SpringerCarlos A Higuera-RuedaBrian C de BeaubienKevin D WarnerAndrew H GlassmanHari K ParvataneniNicolas S PiuzziPublished in: The Journal of arthroplasty (2024)
The use of IAA is safe with minimal systemic antibiotic exposure. There was no difference in the rates or severity of serious adverse events between groups. Further research is being conducted to examine treatment efficacy.