Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa.
Stefan HeitmeierMayken VisserAdrian TersteegenJulia Dietze-TorresJulia GlunzChristoph GerdesVolker LauxJan StampfussSusanne RoehrigPublished in: Journal of thrombosis and haemostasis : JTH (2022)
Asundexian is a potent oral FXIa inhibitor with antithrombotic efficacy in arterial and venous thrombosis models in prevention and intervention settings, without increasing bleeding.