Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver.
P DongiovanniS StenderA PietrelliR M MancinaA CespiatiS PettaS PelusiP PingitoreS BadialiM MaggioniV MannistoS GrimaudoR M PipitoneJ PihlajamakiA CraxiM TaubeL M S CarlssonS FargionS RomeoJ KozlitinaLuca Vittorio ValentiPublished in: Journal of internal medicine (2017)
These data suggest that long-term hepatic fat accumulation plays a causal role in the development of chronic liver disease.