Serum Metabolomic Profiling in Aging Mice Using Liquid Chromatography-Mass Spectrometry.

Tong YueHuiling TanYu ShiMengyun XuSihui LuoJian-Ping Weng Jianping Weng

Published in: Biomolecules (2022)

Changes in the metabolism of fatty acids and conjugates, organic acids, and amino acids were identified as metabolic dysregulation related to aging. This study revealed the metabolic profile of aging and provided insights into novel potential therapeutic targets for delaying the effects of aging.

Keyphrases

mass spectrometry
liquid chromatography
fatty acid
single cell
high resolution mass spectrometry
metabolic syndrome
type diabetes
drug delivery
cancer therapy
adipose tissue
skeletal muscle