GFI1 regulates chromatin state essential in human endothelial-to-haematopoietic transition.

Baoqiang KangTian ZhangKe HuangTianyu WangYuhang LiYuchan MaiJinbing LiShiying DangZhishuai ZhangWenhao HuangJunwei WangMinghui GaoYi WangGuangjin Pan

Published in: Cell proliferation (2022)

Together, our findings reveal an essential role of GFI1 mediated epigenetic mechanism underlying human EHT during hematopoiesis.

Keyphrases

endothelial cells
gene expression
induced pluripotent stem cells
genome wide
dna methylation
pluripotent stem cells
dna damage
transcription factor
single cell