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A prospective, randomized, open-label, parallel trial comparing the efficacy of α-blocker or 5α-reductase inhibitor withdrawal to continued combination therapy on the maintenance of lower urinary tract symptoms in men with benign prostatic hyperplasia.

Kwang-Suk LeeJeong Woo YooDae Ho KimSoyoung JeonJuyeon YangByung Ha ChungKyo Chul Koo
Published in: The Prostate (2023)
In patients with BPH/LUTS who are reluctant to continue combination therapy, AB or 5ARI withdrawal may be offered in men with improvement in IPSS-T by at least seven points and reduction in PV by at least 20%.
Keyphrases
  • combination therapy
  • lower urinary tract symptoms
  • benign prostatic hyperplasia
  • open label
  • phase iii
  • phase ii
  • clinical trial
  • study protocol
  • middle aged
  • randomized controlled trial
  • squamous cell carcinoma