[Influence of CYP3A4, CYP3A5, and NR3C1 genes polymorphism on the effectiveness of glucocorticoid therapy in patients with endocrine ophthalmopathy].

A F Brovkina Dmitry Alekseevich Sychev O S Toropova

Published in: Vestnik oftalmologii (2020)

Results of pharmacogenetic testing of the gene for the glucocorticoid receptor NR3C1 and cytochrome P450 do not provide a reliable confirmation of the influence of the polymorphism of the studied genes on the effectiveness of glucocorticoid therapy in patients with endocrine ophthalmopathy.

Keyphrases

genome wide
genome wide identification
randomized controlled trial
systematic review
genome wide analysis
bioinformatics analysis
copy number
gene expression
cell therapy
binding protein