Joint Tumor Bud-MMP/TIMP Count at the Invasive Front Improves the Prognostic Evaluation of Invasive Breast Carcinoma.
Luis O GonzálezNoemi EiroMaría FraileRosario SánchezAlejandro AndicoecheaSilvia Fernández-FrancosJose SchneiderFrancisco J VizosoPublished in: Biomedicines (2021)
High-grade tumor budding is associated with a more aggressive tumor phenotype, which, combined with MMP/TIMP expression by stromal cells at the invasive front of the tumor, identifies patients with poor prognosis.