Oncogenic Long Non-coding RNA LINC02283 Enhances PDGF Receptor A mediated Signaling and Drives Glioblastoma Tumorigenesis.

Anshika GoenkaXiao SongDeanna TiekRebeca Piatniczka IglesiaMinghui LuChang ZengCraig M HorbinskiWei ZhangBo HuShi-Yuan Cheng

Published in: Neuro-oncology (2023)

Our results provide strong evidence of LINC02283 as a regulator of PDGFRA oncogenic activity and GBM malignancy and support the potential of lncRNAs as possible therapeutic targets.

Keyphrases

long non coding rna
transcription factor
poor prognosis
smooth muscle
genome wide identification
network analysis
vascular smooth muscle cells
binding protein
climate change
genome wide analysis