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Oncogenic Long Non-coding RNA LINC02283 Enhances PDGF Receptor A mediated Signaling and Drives Glioblastoma Tumorigenesis.

Anshika GoenkaXiao SongDeanna TiekRebeca Piatniczka IglesiaMinghui LuChang ZengCraig M HorbinskiWei ZhangBo HuShi-Yuan Cheng
Published in: Neuro-oncology (2023)
Our results provide strong evidence of LINC02283 as a regulator of PDGFRA oncogenic activity and GBM malignancy and support the potential of lncRNAs as possible therapeutic targets.
Keyphrases
  • long non coding rna
  • transcription factor
  • poor prognosis
  • smooth muscle
  • genome wide identification
  • network analysis
  • vascular smooth muscle cells
  • binding protein
  • climate change
  • genome wide analysis