Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes.
Federico CamiciaAna María CelentanoMalcolm E JohnsJohn D ChanLucas L MaldonadoHugo Rolando VacaNicolás Di SierviLaura KamentezkyAna M GamoSilvia Ortega-GutierrezMar Martin-FontechaCarlos DavioJonathan S MarchantMara Cecilia RosenzvitPublished in: PLoS neglected tropical diseases (2018)
These data provide the first functional report of GPCRs in parasitic cestodes. The serotoninergic GPCRs characterized here may represent novel druggable targets for antiparasitic intervention.