The Intervention Probability Curve: Modeling the Practical Application of Threshold-Guided Decision-Making, Evaluated in Lung, Prostate, and Ovarian Cancers.

Michael N Kammer Dianna J Rowe Stephen A Deppen Eric L Grogan Alexander M Kaizer Anna E Baron Fabien Maldonado

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2022)

We propose that consideration of IPCs will yield significant insights into the practical relevance of threshold-based management strategies and could provide a novel method to estimate the actual clinical utility of novel biomarkers.

Keyphrases

decision making
prostate cancer
randomized controlled trial
benign prostatic hyperplasia
young adults