Treatment Strategies in Early Rheumatoid Arthritis Methotrexate Management: Results From a Prospective Cohort.

Cristiano Soares de MouraOrit SchieirMarie-France Valois J Carter Throne Susan J Bartlett Janet E Pope Carol A Hitchon Gilles BoireBoulos HaraouiGlen Stewart HazlewoodEdward C KeystoneDiane TinVivian P Bykerk Sasha Bernatskynull null

Published in: Arthritis care & research (2020)

We found large variability in the way MTX-based therapies are prescribed in clinical practice. Our findings support the use of SC MTX monotherapy or MTX combination as initial therapy. For subsequent treatment after initial MTX-based therapy, those patients initiating either biologics or triple therapy had a longer time to treatment change than oral MTX monotherapy.

Keyphrases

rheumatoid arthritis
combination therapy
end stage renal disease
clinical practice
ejection fraction
chronic kidney disease
newly diagnosed
open label
high dose
randomized controlled trial
clinical trial
prognostic factors
peritoneal dialysis
mesenchymal stem cells
study protocol