Tofacitinib in acute severe ulcerative colitis (TACOS): A randomized controlled trial: Tofacitinib in ASUC.
Arshdeep SinghManjeet Kumar GoyalVandana MidhaRamit MahajanKirandeep KaurYogesh Kumar GuptaDharmatma SinghNamita BansalRamandeep KaurShivam KalraOmesh GoyalVarun MehtaAjit SoodPublished in: The American journal of gastroenterology (2023)
In patients with ASUC, combination of tofacitinib and corticosteroids improved treatment responsiveness and decreased the need for rescue therapy. Trial registration number: ISRCTN42182437.
Keyphrases
- ulcerative colitis
- rheumatoid arthritis
- liver failure
- drug induced
- clinical trial
- study protocol
- respiratory failure
- phase iii
- early onset
- randomized controlled trial
- stem cells
- intensive care unit
- combination therapy
- aortic dissection
- open label
- smoking cessation
- extracorporeal membrane oxygenation
- mechanical ventilation