IgE-autoantibodies against CENP-A/B and topo-I occur in SSc underlining the concept that SSc may be a T helper cell type 2 mediated disease. IgE-anti-CENP-A-antibodies correlated with disease activity, but this has to be confirmed in larger studies.
Keyphrases
- systemic sclerosis
- systemic lupus erythematosus
- disease activity
- interstitial lung disease
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- dendritic cells
- juvenile idiopathic arthritis
- regulatory t cells
- case control
- immune response
- real time pcr
- idiopathic pulmonary fibrosis
- quantum dots