Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.

Joel CastroLuke GrundyAnnemie DeiterenAndrea M HarringtonTracey O'DonnellJessica MaddernJessi MooreSonia Garcia-CaraballoGrigori Y RychkovRilei YuQuentin KaasDavid J CraikDavid J Adams Stuart M Brierley

Published in: British journal of pharmacology (2018)

This article is part of a themed section on Recent Advances in Targeting Ion Channels to Treat Chronic Pain. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.12/issuetoc.

Keyphrases

chronic pain
abdominal pain
mouse model
pain management
cancer therapy
molecular docking
ultrasound guided
ulcerative colitis
postoperative pain
drug delivery