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Relationship between white matter integrity and post-traumatic cognitive deficits: a systematic review and meta-analysis.

Jie ZhangLiang TianLi ZhangRuidong ChengRuili WeiFangping HeJuebao LiBen-Yan LuoXiangming Ye
Published in: Journal of neurology, neurosurgery, and psychiatry (2018)
FA is the most sensitive metric for detecting post-TBI cognitive decline across various domains. Representative white matter regions, such as the CC and IC, perform better than whole-brain white matter for reflecting a wide range of cognitive domains, including memory, attention and executive functions. Moreover, the fornix and cingulum particularly reflect memory function. They yield insights into particular imaging indicators that have neuropsychological value.
Keyphrases
  • white matter
  • cognitive decline
  • working memory
  • mild cognitive impairment
  • multiple sclerosis
  • traumatic brain injury
  • high resolution
  • cross sectional
  • subarachnoid hemorrhage
  • fluorescence imaging