Natural history of familial cerebral cavernous malformation syndrome in children: a multicenter cohort study.

Ana Filipa Geraldo César Augusto Pinheiro Ferreira Alves Aysha Luis Domenico Tortora Joana Guimarães Daisy Abreu Sofia Reimão Marco Pavanello Patrizia de Marco Marcello Scala Valeria Capra Rui Vaz Andrea Rossi Erin Simon Schwartz Kshitij Mankad Mariasavina Severino

Published in: Neuroradiology (2022)

The 5-year annual and cumulative symptomatic hemorrhagic risk in our pediatric FCCM cohort equals the overall risk described in children and adults with all types of CCM. Imaging features at first brain MRI may help to predict potential symptomatic hemorrhage at 5-year follow-up.

Keyphrases

young adults
magnetic resonance imaging
high resolution
subarachnoid hemorrhage
cerebral ischemia
early onset
white matter
cross sectional
resting state
multiple sclerosis
case report
mass spectrometry
functional connectivity
blood brain barrier
photodynamic therapy
diffusion weighted imaging