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Thiopurines vs methotrexate: Comparing tolerability and discontinuation rates in the treatment of inflammatory bowel disease.

Abhinav VasudevanNina ParthasarathyDanny ConSteven NicolaidesRoss ApostolovAyushi ChauhanMaria BisharaRaphael P LuberNeetima JoshiAnna WanJames A RickardTony LongDeclan ConnoleyMiles Patrick SparrowPeter R GibsonDaniel R Van Langenberg
Published in: Alimentary pharmacology & therapeutics (2020)
Discontinuation of methotrexate occurred at rates twice that of dose-optimised thiopurine therapy.
Keyphrases
  • high dose
  • open label
  • randomized controlled trial
  • clinical trial
  • combination therapy
  • replacement therapy
  • ulcerative colitis
  • study protocol
  • cell therapy
  • placebo controlled
  • smoking cessation