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The initial effectiveness of liposomal amphotericin B (AmBisome) and miltefosine combination for treatment of visceral leishmaniasis in HIV co-infected patients in Ethiopia: A retrospective cohort study.

Charles AbongomeraErmias DiroAlan PereiraJozefien BuyzeKolja StilleFareed AhmedJohan van GriensvenKoert Ritmeijer
Published in: PLoS neglected tropical diseases (2018)
Initial parasitological failure rates were very low with AmBisome and miltefosine combination therapy. This regimen seems a suitable treatment option. Knowledge of predictors of poor outcome may facilitate better management. These findings remain to be confirmed in clinical trials.
Keyphrases
  • combination therapy
  • clinical trial
  • randomized controlled trial
  • healthcare
  • systematic review
  • human immunodeficiency virus
  • hiv infected
  • antiretroviral therapy
  • hiv testing
  • south africa