Oxidative stress and nitrate/nitrite (NOx) status following citrulline supplementation in type 2 diabetes: a randomised, double-blind, placebo-controlled trial.
Samaneh AziziMehrangiz Ebrahimi-MameghaniM MobasseriN KaramzadReza MahdaviPublished in: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association (2020)
The results of the present study show the positive effects of citrulline supplementation with respect to attenuating FBS levels and oxidative stress, as well as boosting NOx status, in patients with T2DM.
Keyphrases
- double blind
- oxidative stress
- placebo controlled
- type diabetes
- clinical trial
- nitric oxide
- study protocol
- dna damage
- reactive oxygen species
- diabetic rats
- glycemic control
- ischemia reperfusion injury
- induced apoptosis
- open label
- phase iii
- phase ii
- insulin resistance
- randomized controlled trial
- signaling pathway
- drinking water
- adipose tissue