A comprehensive approach to predicting weight gain and therapy response in psychopharmacologically treated major depressed patients: A cohort study protocol.
Maria S SimonBarbara B BartonCatherine GlockerRichard MusilPublished in: PloS one (2022)
Patient and physician expectancies regarding the primary outcomes and non-random sampling may affect internal validity and external validity, respectively. Through the prospective and naturalistic design, results will gain relevance to clinical practice. Examining the predictive value of patient profiles for weight gain and treatment response during pharmacotherapy will allow for targeted adjustments before and concomitantly to the start of treatment.
Keyphrases
- weight gain
- body mass index
- birth weight
- end stage renal disease
- clinical practice
- newly diagnosed
- study protocol
- case report
- weight loss
- ejection fraction
- randomized controlled trial
- primary care
- emergency department
- chronic kidney disease
- peritoneal dialysis
- stem cells
- type diabetes
- patient reported outcomes
- mesenchymal stem cells
- metabolic syndrome
- open label
- adipose tissue
- physical activity
- combination therapy
- cell therapy
- skeletal muscle
- bone marrow
- replacement therapy