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Sulforaphane Effects on Cognition and Symptoms in First and Early Episode Schizophrenia: A Randomized Double-Blind Trial.

Gangrui HeiRobert C SmithRanran LiJianjun OuXueqing SongYingjun ZhengYiqun HeJen ArriazaJed W FaheyBrian CornblattDongyu KangYe YangJing HuangXiaoyi WangKristin CadenheadMimei ZhangJohn M DavisJingping ZhaoHua JinRenrong Wu
Published in: Schizophrenia bulletin open (2022)
Although the primary outcome was not significant, improvement in three domains of the MATRICS battery, suggests a positive cognitive effect on some cognitive functions, which warrants further clinical trials to further assess whether sulforaphane may be a useful adjunct for treating some types of cognitive deficits in schizophrenia.
Keyphrases
  • clinical trial
  • bipolar disorder
  • phase iii
  • phase ii
  • double blind
  • study protocol
  • open label
  • placebo controlled
  • mild cognitive impairment
  • randomized controlled trial
  • physical activity