Upregulation of miR-3195, miR-3687 and miR-4417 is associated with castration-resistant prostate cancer.

C G H RönnauS FussekF P SmitT W AaldersOnno van Hooij Pedro Caetano PintoM BurchardtJack A Schalken Gerald W Verhaegh

Published in: World journal of urology (2021)

We have identified several novel deregulated miRNAs in CRPC tissue, including two microRNAs that are potentially involved in tumor invasion. Our data support the hypothesized involvement of miRNAs in PCa tumorigenesis and progression to CRPC. The applicability of these miRNAs as novel biomarkers for CRPC remains to be further investigated.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
poor prognosis
cell migration
high resolution