The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype.
Shantel Hebert-MageeHan YuMichael BehringTrafina JadhavChandrakumar ShanmugamAndra FrostIsam-Eldin EltoumSooryanarayana VaramballyUpender MannePublished in: PloS one (2019)
For BCs, the survival effect of SNP72 combined with a p53 missense mutation is dependent on race and molecular subtype. Although such a mutation is a marker of poor prognosis, it is relevant to identify the variant Pro/Pro in the case of AAs, especially those with luminal subtypes of BC.