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An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells.

Nahyun KwonMyoung Ki ChoSang Jun ParkDayoung KimSang-Jip NamLei CuiHwan Myung KimJuyoung Yoon
Published in: Chemical communications (Cambridge, England) (2017)
A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.
Keyphrases
  • fluorescent probe
  • living cells
  • endothelial cells
  • high resolution
  • induced pluripotent stem cells
  • loop mediated isothermal amplification
  • pluripotent stem cells
  • label free
  • quantum dots