Phenobarbital Versus Benzodiazepines for the Treatment of Severe Alcohol Withdrawal.

Katherine M Kessel Logan M OlsonDerek A KruseElizabeth R LydenKelsey E WhistonMindy M BlodgettAlena A Balasanova

Published in: The Annals of pharmacotherapy (2024)

Scheduled phenobarbital was associated with decreased hospital LOS compared to benzodiazepines for SAWS. This was the first study to compare outcomes of fixed-dose, nonoverlapping phenobarbital to benzodiazepines in patients with clearly defined SAWS and details a readily implementable protocol.

Keyphrases

randomized controlled trial
healthcare
emergency department
combination therapy
alcohol consumption
acute care
adverse drug
glycemic control
replacement therapy
smoking cessation